COVID-19 may double risk of severe complications in pregnancy, according to new study

HAVE ON A PREGNANT WOMAN AND HER UNBORN CHILD. # ## <XINA GARCIA // 7 MONTHS PREGNANT> 7:51 A LITTLE SC EDAR BECAUSE I DID ACTUALLY GET COVID WHILE PREGNANT AND IT WAS THE FIRST TIME I EVER GOT COVID 7:59 .. AT 7 MONTHS PREGNANT...THE NEW RESEARCH I AS CONCERN FOR XINA GARCIA....SHE WORRIES ABOUT POSSIBLE COMPLICATIONS THAT COMES WITH CATCHING COVID WHILE PREGNANT... <RACHEL MCCATHY BECK// SVMH GYNECOLOGIST > 01:34 THIS NEW STUDY THAT JUST CAME OUT IS IS HELPING US TO UNDERSTAND EVEN MORE SPECIFICAL HLYOW COV ID INFECTION DOES ACTUALLY NEGATIVELY AFFECT OUR PREGNANT POPULATION. 01:49 . THE NEW DATCOA MING OUT OF A LARGE STUDY CONSISTING OF 43,886 WOMEN WHO GAVE BIRTH AT KAISER PERMANENTE IN NORTHERN CALIFORNIA. .. CONDUCTED BETWEEN MARCH 1ST 2020.. AND MARCH 16TH 2021 BEFORE VACCINES WERE AVAILABL.. E. <RACHEL MCCATHY BECK// SVMH GYNECOLOGIST > 05:59 THE COVID INFEN IOCT DOES NOT PASS FROM MOTHER TO CHILD IN UTERO, SO THAT'S THAT'S A GOOD THING. 6:07 BUT THERE ARE DEFINITELY EFFECTS ON THE BABY. IF THIS BABY HAS TO BE DELIVERED PRETERM 6:14 AND BABIES BORN PREMATURELY DO HAVE A GREATER RISK FOR BRAIN OR HEART PROBLEMS....AND THERE ARE CERTAINLY RISKS FOR MOM, TOO. <RACHEL MCCATHY BECK // SVMH GYNECOLOGIST > 02:07 A DOUBLING OF THRIE SK OF SUCH COMPLICATIONS AS SEVERE MATERNAL MORTALIT SY,EVE ER MATERNAL MORBIDITY, THINGS LIKE SEPSIS. IT ALSO SHOWED AN INCREASED RISK FOR PRETERM DELIVERY AND THROMBOEMBOLISM. 02:29 .. THE STU FDYOUND THAT COVID INFECTED PREGNANT WOMEN WERE THREE TIMES ME LIKELY TO DEVELOP SERIOUS BLOOD CLOTS. BUT GARCIA IS STAYING OPTIMISTIC..GR. ATEFUL THAT SHE GOT VACCINATED AND BOOSTED.... <XINA GARCIA // 7 MONTHS PREGNA> NT 1:10:03 I FEEL LIKE GETTING THAT BEFORE I WAS PREGNANT, HELPED WITH THE COVID SY MPTOMS. IT WASN'T SO SEVERE BECAUSE MY SPOU

Pregnant patients who tested positive for the coronavirus had more than double the risk of poor outcomes than patients who did not test positive for the virus, according to a new study.Conducted by Kaiser Permanente in Northern California, the study looked at 43,866 pregnant individuals who delivered between March 2020 and March 2021, of whom 1,332 had a coronavirus infection during their pregnancy. Notably, the time period that was studied took place before vaccines against the virus were available to the general population.The patient population was racially and ethnically diverse, with 33.8% white, 28.4% Hispanic or Latino, 25.9% Asian or Pacific Islander, 6.5% Black, 0.3% American Indian or Alaska Native, and 5% multiracial or unknown race and ethnicity.Poor outcomes included preterm birth, venous thromboembolism (blood clot), and severe maternal morbidity. Severe maternal morbidity is a composite outcome that includes 21 severe conditions occurring during pregnancy, the most frequent in patients who tested positive for the coronavirus being acute respiratory distress syndrome and sepsis The study found twice the risk for preterm birth for those testing positive for coronavirus. COVID-positive patients were also three times more likely to suffer a blood clot and 2 1/2 times more likely to have a severe maternal morbidity.Dr. Assiamira Ferrara, the lead author of the study, said she was not surprised by the findings, particularly regarding preterm births and blood clots."Given prior evidence of other infections and various inflammatory cytokines leading to preterm birth, the association between SARS-CoV-2 infection and preterm birth was physiologically plausible," Dr. Ferrara, a senior research scientist and associate director at Kaiser, said."COVID-19 is associated with abnormal coagulation profiles," Dr. Ferrara continued. "This is a serious concern for pregnant patients since pregnancy is associated with a hypercoagulable state, which might be exacerbated by SARS-CoV-2 infection."Coagulation refers to the process by which blood turns from a liquid to a gel-like consistency, forming a blood clot. Dr. Ferrara also added that pre-existing conditions "did not have an effect on the differences in perinatal complications between the people with positive tests and those without."As for variants, the study was conducted well before omicron, and most likely before delta was prevalent in the U.S. Dr. Ferrara said that other studies, though, have shown that the variants could increase the risk in pregnant patients."Some recent studies have reported that pregnant women with a SARS-CoV-2 infection during the time the delta variant was predominant were more likely to die or need mechanical ventilation than women with a SARS-CoV-2 infection before the delta variant became predominant," she said.Dr. Ferrara said one of the most important takeaways from this study should be the importance of pregnant individuals getting vaccinated."People planning a pregnancy and pregnant patients can maintain their health in many ways, and now we can add vaccination against COVID-19 as one of the most important," she said. "Other research has shown that vaccination during pregnancy is safe."

Pregnant patients who tested positive for the coronavirus had more than double the risk of poor outcomes than patients who did not test positive for the virus, according to a new study.

Conducted by Kaiser Permanente in Northern California, the study looked at 43,866 pregnant individuals who delivered between March 2020 and March 2021, of whom 1,332 had a coronavirus infection during their pregnancy.

Notably, the time period that was studied took place before vaccines against the virus were available to the general population.

The patient population was racially and ethnically diverse, with 33.8% white, 28.4% Hispanic or Latino, 25.9% Asian or Pacific Islander, 6.5% Black, 0.3% American Indian or Alaska Native, and 5% multiracial or unknown race and ethnicity.

Poor outcomes included preterm birth, venous thromboembolism (blood clot), and severe maternal morbidity.

Severe maternal morbidity is a composite outcome that includes 21 severe conditions occurring during pregnancy, the most frequent in patients who tested positive for the coronavirus being acute respiratory distress syndrome and sepsis

The study found twice the risk for preterm birth for those testing positive for coronavirus. COVID-positive patients were also three times more likely to suffer a blood clot and 2 1/2 times more likely to have a severe maternal morbidity.

Dr. Assiamira Ferrara, the lead author of the study, said she was not surprised by the findings, particularly regarding preterm births and blood clots.

"Given prior evidence of other infections and various inflammatory cytokines leading to preterm birth, the association between SARS-CoV-2 infection and preterm birth was physiologically plausible," Dr. Ferrara, a senior research scientist and associate director at Kaiser, said.

"COVID-19 is associated with abnormal coagulation profiles," Dr. Ferrara continued. "This is a serious concern for pregnant patients since pregnancy is associated with a hypercoagulable state, which might be exacerbated by SARS-CoV-2 infection."

Coagulation refers to the process by which blood turns from a liquid to a gel-like consistency, forming a blood clot.

Dr. Ferrara also added that pre-existing conditions "did not have an effect on the differences in perinatal complications between the people with positive tests and those without."

As for variants, the study was conducted well before omicron, and most likely before delta was prevalent in the U.S. Dr. Ferrara said that other studies, though, have shown that the variants could increase the risk in pregnant patients.

"Some recent studies have reported that pregnant women with a SARS-CoV-2 infection during the time the delta variant was predominant were more likely to die or need mechanical ventilation than women with a SARS-CoV-2 infection before the delta variant became predominant," she said.

Dr. Ferrara said one of the most important takeaways from this study should be the importance of pregnant individuals getting vaccinated.

"People planning a pregnancy and pregnant patients can maintain their health in many ways, and now we can add vaccination against COVID-19 as one of the most important," she said. "Other research has shown that vaccination during pregnancy is safe."

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